Effects of Coenzyme Q10 on the Antioxidant System in Blood and Liver of Laying Hens

The objective of this study was to investigate the effects dietary coenzyme Q10 (CoQ10) sources on antioxidant defense system in blood and liver laying hens. Thirty-six 40-wk old Lohmann Brown hens were randomly assigned three groups based body weight, with four cages layers each. Laying divided into one following groups: control (CON), powdered CoQ10 (PCoQ, 100 mg/kg diet), emulsified (ECoQ, diet). All fed a diet or supplemented ad libitum for five weeks. There no differences weight gain, organ weights among treatment groups, including spleen. total power (TAP) ECoQ group increased (P<0.05) by approximately 2-fold compared that CON group. However, there significant difference TAP levels between PCoQ although decreasing trend (P<0.13) observed mRNA expression specific activities superoxide dismutase, glutathione peroxidase, catalase not affected type CoQ10. hepatic lipid peroxidation lower than In conclusion, decreased without affecting enzymes, suggesting might be more applicable as an active supplement